Within a analyze in breast cancer cells, The mix of lapatinib, a dual HER2/neu and EGFR tyrosine kinase inhibitor, with INK128 prevented both HER2 and HER3 phosphorylation induced by INK128 and developed synergistic induction of cell Dying in several HER2-optimistic cell traces immune to trastuzumab and lapatinib. In vivoSummary Lycorine is the mos